Quinolines and derivatives
Aobchem 7-Chloro-2-methylquinoline | ≥95% | CAS 4965-33-7 | C10H8ClN | 25g
7-Chloro-2-methylquinoline | ≥95% | CAS 4965-33-7 | C10H8ClN | 25g
![Medchemexpress LLC Ethanesulfonic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]- | 1817735-43-5 | 99.5% | 257.30 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Ethanesulfonic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]- | 1817735-43-5 | 99.5% | 257.30 | 25 MG
Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to a target protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Intended for research use only
- Appearance: oil, colorless to light yellow
- Target: PEGs
- Storage: -20°C under nitrogen
Aobchem 7-Chloro-4-quinolinecarboxylic acid | ≥95% | CAS 13337-66-1 | C10H6ClNO2 | 5g
7-Chloro-4-quinolinecarboxylic acid | ≥95% | CAS 13337-66-1 | C10H6ClNO2 | 5g
Aobchem 7-Chloro-2-methylquinoline | ≥95% | CAS 4965-33-7 | C10H8ClN | 100g
7-Chloro-2-methylquinoline | ≥95% | CAS 4965-33-7 | C10H8ClN | 100g
Medchemexpress LLC Acotiamide monohydrochloride trihydrate | 773092-05-0 | 99.79% | 1 ML
Acotiamide monohydrochloride trihydrate is an orally active, selective, and reversible acetylcholinesterase (AChE) inhibitor with an IC50 of 1.79 μM. It enhances gastric contractility and accelerates delayed gastric emptying, making it a potential research compound for functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory conditions.
- Enhances gastric contractility and accelerates delayed gastric emptying.
- Reduces expression levels of IκB-α phosphorylation in stimulated macrophage cell lines.
- Significantly reduces TNF-α and IL-6 productions in stimulated NR8383 cells.
- Increases postprandial gastric motility index in a dose-dependent manner in vivo.
- Improves functional dyspepsia by inhibiting AChE.
Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | >98.36% | 10 G
Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It acts as a potent, orally active, and selective cytochrome P450db inhibitor. Additionally, Quinidine is a K+ channel blocker with an IC50 of 19.9 μM and is capable of inducing apoptosis. This compound can also be utilized for malaria research.
- Antiarrhythmic agent.
- Potent, orally active, selective cytochrome P450db inhibitor.
- K+ channel blocker with an IC50 of 19.9 μM.
- Can induce apoptosis.
- Used for malaria research.
Medchemexpress LLC Gemifloxacin mesylate | 210353-53-0 | 99.59% | 5 MG
Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. It inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in in vitro efficacy study, particularly Streptococci and Staphylococci. It has been used in the research of respiratory tract infections.
- Inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities.
- Potent antibacterial activities against gram-positive bacteria in in vitro efficacy study, particularly Streptococci and Staphylococci.
- Used in the research of respiratory tract infections.
Aobchem Methyl 2 3-dimethoxy-6-fluorobenzoate | ≥97% | CAS 1260793-27-8 | C10H11FO4 | 5g
Methyl 2 3-dimethoxy-6-fluorobenzoate | ≥97% | CAS 1260793-27-8 | C10H11FO4 | 5g
Aobchem 2 3-Dimethoxy-6-fluorophenylboronic acid | ≥97% | CAS 1451392-13-4 | C8H10BFO4 | 5g
2 3-Dimethoxy-6-fluorophenylboronic acid | ≥97% | CAS 1451392-13-4 | C8H10BFO4 | 5g
Medchemexpress LLC Vinburnine | 4880-88-0 | 99.8% | 200 MG
Vinburnine is a vinca alkaloid and a metabolite of vincamine, which acts as a vasodilator. It is intended for research use only.
- Allosteric modulator of muscarinic receptors M1-M4.
- Exhibits an anti-amnesia effect in a scopolamine-induced mouse amnesia model.
- Promotes erythrocyte glycolysis, increases erythrocyte ATP and 2,3-diphosphoglycerol content, and improves erythrocyte deformability and tissue oxygen delivery.
![eMolecules 702-69-2 | 7-Methyl-1,4-dioxaspiro[4.5]decan-8-one | Ambeed | MFCD13189957 | 170.208 | C9H14O3 | 97.000 | CC1CC2(CCC1=O)OCCO2 | 5g | 524990432](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000169750.jpg-250.jpg)
eMolecules 702-69-2 | 7-Methyl-1,4-dioxaspiro[4.5]decan-8-one | Ambeed | MFCD13189957 | 170.208 | C9H14O3 | 97.000 | CC1CC2(CCC1=O)OCCO2 | 5g | 524990432
7-Methyl-1,4-dioxaspiro[4.5]decan-8-one | Ambeed | 702-69-2 | MFCD13189957 | 170.208 | C9H14O3 | 97.000 | CC1CC2(CCC1=O)OCCO2 | 5g | 524990432
Apexbio Technology LLC Dp44mT 152095-12-0 200mg
Dp44mT (CAS 152095-12-0) is a small molecule iron chelator that selectively inhibits topoisomerase II a critical enzyme involved in chromosome segregation DNA replication and transcription In human breast cancer MDA-MB-231 cells Dp44mT exhibits a GI50 of approximately 100 nmol/L Experiments indicate that its cytotoxic effects are reduced in cells with diminished topoisomerase II expression underscoring target specificity Dp44mT treatment leads to the formation of covalent DNA-topoisomerase II complexes without affecting topoisomerase I or II These properties support its utility in studies on DNA damage enzymatic selectivity and mechanisms underlying cancer cell cytotoxicity
Medchemexpress LLC Gemifloxacin (mesylate) | 210353-53-0 | 99.7% | 50 MG
Gemifloxacin mesylate is an orally active, broad-spectrum quinolone antibacterial antibiotic that inhibits DNA synthesis by targeting DNA gyrase and Topoisomerase IV activities. It exhibits potent antibacterial activities against gram-positive bacteria, particularly Streptococci and Staphylococci, and has been utilized in research for respiratory tract infections.
- Inhibits DNA gyrase and Topoisomerase IV activities
- Potent antibacterial activities against gram-positive bacteria
- Effective against Streptococci and Staphylococci
- Used in respiratory tract infection research